Complex Intramolecular Mechanics of G-actin — An Elastic Network Study
by Markus Düttmann, Markus Mittnenzweig, Yuichi Togashi, Toshio Yanagida, Alexander Mikhailov
Year:
2012
Publication:
PLOS One
Abstract:
Systematic numerical investigations of conformational motions in single actin molecules were performed by employing a simple elastic-network (EN) model of this protein. Similar to previous investigations for myosin, we found that G-actin essentially behaves as a strain sensor, responding by well-defined domain motions to mechanical perturbations.
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Brief introduction of the dida co-author(s) and relevance for dida's ML developments.
About the Co-Author
Markus is a physicist and entrepreneur with a deep understanding of mathematics, statistics, and machine learning. He leverages his unique background to guide dida’s clients toward data-driven solutions that optimize their operations and maximize impact.
Prior to dida, Markus founded the programmatic buying platform realzeit and focused on software and deep tech investments at the venture capital firms Nauta Capital and DTCF.